Functional MRI of impaired finger dexterity in Parkinson's disease

Losing dexterity: patterns of impaired coordination of finger movements in musician’s dystonia

Extensive training can bring about highly-skilled action, but may also impair motor dexterity by producing involuntary movements and muscular cramping, as seen in focal dystonia (FD) and tremor. To elucidate the underlying neuroplastic mechanisms of FD, the present study addressed the organization of finger movements during piano performance in pianists suffering from the condition. Principal c...

Impaired Arm Function and Finger Dexterity in a Nonhuman Primate Model of Stroke

The World Health Organization reports that stroke claims 6.2 million lives each year. There are ≈5.4 million stroke survivors with ≈80% requiring hand therapy. The estimated economic burden for stroke exceeds $56.8 billion per year in the United States alone. Acute thrombolysis has a significant impact on the management of stroke, with a therapeutic window that may extend ≤6 hours with intra-ar...

A test of fine finger dexterity.

The lack of instruments available for the measurement of fine dexterity (i.e., speed of interdigital manipulation) implies a gap not only in the occupational therapist's ability to quantify and deal precisely with patients' problems in this area, but also in the knowledge base of occupational therapy itself. The Rosenbusch Test of Finger Dexterity (developed by Doris F. Rosenbusch, MA, OTR), a ...

Functional MRI in Alzheimer’s Disease

Poor dopaminergic response of impaired dexterity in Parkinson's disease: Bradykinesia or limb kinetic apraxia?

Patients with Parkinson's disease (PD) often show impaired manual dexterity even when being only minimally bradykinetic, suggesting that they may have limb kinetic apraxia (LKA), that is, a loss of fine motor skill not explained by elemental motor deficits. To explore this dissociation, we investigated the differential dopaminergic responsiveness of dexterity and bradykinesia in PD. Twelve pati...